Medication Patterns Analysis of Sun Wei in the Treatment of Chronic Kidney Disease with Hyperuricemia Based on Data Mining
XIE Jiadong
HE Weiming
ZHAO Yufeng
HE Jiayi
HU Kongfa
SUN Wei
Abstract：Objective To analyze Professor Sun Wei's prescription and medication law in the treatment of chronic kidney disease(CKD)complicated with hyperuricemia based on data mining technology.Methods We collected the medical records of patients with CKD complicated with hyperuricemia treated by Professor Sun Wei of Jiangsu Hospital of Traditional Chinese Medicine from 2016 to 2022,established a database,and used data mining software to conduct drug frequency,flavor,meridian tropism statistics,frequent pattern analysis,clustering,and complex network analysis.Results A total of 349 prescriptions were included,involving 143 Chinese herbal medicine,with a total frequency of 8438 times.High-frequency drugs include Astragali Radix(Huangqi),Perillae Caulis(Zisugeng),Atractylodis Macrocephalae Rhizoma(Baizhu),Pyrrosiae Folium(Shiwei),Curcumae Radix(Yujin),Polygoni Cuspidati Rhizoma Et Radix(Huzhang),Codonopsis Radix(Dangshen),Eucommiae Cortex(Duzhong),Angelicae Sinensis Radix(Danggui),Dipsaci Radix(Xuduan),Chuanxiong Rhizoma(Chuanxiong),etc.They mainly focused on tonifying deficiency,diuretic and hygroscopic effects,and promoting blood circulation and removing blood stasis.The nature and flavour are mostly warm and sweet,belonging to liver,spleen,lung,kidney and stomach meridian.Commonly used drug combinations include"Astragali Radix(Huangqi),Atractylodis Macrocephalae Rhizoma(Baizhu),Codonopsis Radix(Dangshen),Perillae Caulis(Zisugeng)","Eucommiae Cortex(Duzhong),Dipsaci Radix(Xuduan)","Pyrrosiae Folium(Shiwei),Smilacis Glabrae Rhizoma(Tufuling)","Angelicae Sinensis Radix(Danggui),Chuanxiong Rhizoma(Chuanxiong),Curcumae Radix(Yujin)",etc.Conclusion Professor Sun Wei considers that the pathogenesis of this disease as"kidney deficiency,dampness and blood stasis",and the treatment prescription primarily focuses on"benefiting the kidney,clearing the benefit and draining the turbid collaterals".
Keywords：Chronic kidney disease complicated with hyperuricemiaSun WeiMedication lawData mining
Publication Date：2024-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 674-679 )