Comparative Analysis of Tianma Gouteng Decoction and Calcium Channel Blockers In Preventive Treatment of Migraine: A Meta Analysis
CAI Yin-he
LU Ke
SUN Wei-peng
WU Zhi-bing
Abstract：Objective: To systematically review the clinical effect and safety of Tianma Gouteng Yin (TGY) for migraine compared to Calcium channel blockers (CCB). Method: Such databases as Pub Med, Cochrane library, CNKI, VIP, Wanfang data and CBM were searched and we carried out meta-analysis and TSA analysis by using Stata 14 version and TSA v0. 9 respectively. Results: Totally 10 RCT including 900 cases were included eventually. The analysis shows that the total effective rate of prophylactic treatment of migraine in TGY increased by 31％ compared to CCB (RR = 1. 31, 95％CI (1. 22, 1. 40) ). The TSA analysis shows that the evidence of the total effective rate is definite. The incidence of adverse reactions was 3. 1％ in the treatment group and 7. 5％ in the control group. Conclusion: The effectiveness and safety of TGY in the treatment of migraine is better than CCB, which has a good long-term effect. But a larger sample, higher quality RCT test are definitely needed for confirming the conclusion.
Keywords：Tianma Gouteng YinCalcium channel blockersmigraineMeta-analysis
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 949-954 )