Thinking About Animal Model of Disease and Syndrome Combination
CHEN Yan-qing
YANG Jing-jing
CAO Zhuo-qing
MA Jing
GUO Lei
QIN Ya-li
Abstract:There are five methods of animal model reproduce which combines diseases with syndromes.The first method is to establish disease models,consistently observe the syndromes that the model appears.The second is to analyze the syndromes of spontaneous animal models of disease.The third,to differentiate the syndromes of the disease models,with the way of differentiating syndrome with formula,The fourth,to diagnose diseases through the testing of specific index,after the syndrome model is established.The fifth method is to superpose disease models and syndrome models.In accordance with the principles of replication of animal models,the paper analyzes the five methods,explores the problems in the animal models combined disease and syndrome,and proposes some solutions.First,when establish animal model,the differences between human and animal models should be taken into consideration.Then we should pay attention to the influence of models established by single factor and multifactor.And the modeling method of the same syndrome should be unified.Finally we should establish a unified evaluation system.
Keywords:Combination of disease and syndromeDiseaseSyndromeAnimal model
Publication Date:2017-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 628-629,705 )