Perioperative Treatment to Improve the Survival Rate of Rat Model of Heart Failure after Infarction Induced by Coronary Artery Ligation
ZHOU Zheng
CHEN Zi-xin
CHEN Jie
SHEN Xiao-xiao
TANG Ya-qin
XIAN Shao-xiang
Abstract：Objective:To improve the survival of the left anterior descending coronary artery ligation induced postmyocardial infarction heart failure rat models by optimizing preoperative management.Methods:During repeatedly modeling process,we tried to promote the models survival with appropriate animals screening,breathing management regulation,surgical operation improvement and preoperative nursing.Meanwhile we attempted to control the level of heart failure through regulating the ligation site.Results:Gradually improvement of models survival and distinct weakening of heart function were expressed by various regulations.Conclusions:Preoperative management optimization can significantly improve the survival of post-myocardial infarction heart failure rat models,thereby suggesting a more stable heart failure model-making protocol for further experiments.
Keywords：Post-myocardial infarction heart failureRatCoronary artery ligationSurvival
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 335-337 )