Establish the Model of Rat of Deficiency of the Kidney-Essence and the Liver-Blood
Abstract：Objective In order to study the mechanism of “The liver and the kidney have a common source of the essence and the blood”,establish the model of rat of deficiency of the kidney-essence and the liver-blood. Method Litters delivered Wistar rats were treated with monosodium glutamate(MSG) dissolved in saline solution. MSG 4mg/g b.wt. was injected s.c. daily from the 2nd to the 10th day after birth. On the 8 weeks, partial hepatectomy was performed by excision of the median and left hepatic lobes according to the method of Higgins and Anderson under pentobarbital anesthesia. Results The degree of liver regeration, MI, the rate of liver weight/body weight, the degree of proliferation of nucleated cells in bone marrow, RBC and Hb were significantly lower than the normal and saline solution control group. Conclusion MSG-rat partial hepatectomy was performed by excision of the median and left hepatic lobes is the model of rat of deficiency of the kidney-essence and the liver-blood.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 51-54 )