Experimental study on YQTLD's effect on bcl-2 expression of cardiac myocyte under hypoxia-reoxygenation
QIU Xing-sheng
CHEN Su-yin
SHEN Jian-gan
HUANG Wei-yi
CHEN Kai
Abstract：Objective:To elucidate whether YQTLD can enhance bcl-2 expression of cardiac myocyte during hypoxiareoxygenation. Methods:cultured neonatal rat cardiac myocyte was treated with 24h hypoxia and 4h reoxygenation, the level of bcl-2 expression was detected by fluorescent immunocytochemistry and assayed by flow cytometry. Results:Experiment showed hypoxia-reoxygenation could induce bcl-2 expression, which could be further enhanced by serum containing YQTLD. Conclusion:It suggest that YQTL may exert benificial effect on cardiac myocyte during hypoxiareoxygenation, this underlies one of its mechanisms to treat ischemic heart disease.
Machine-generated Keywords：
Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 38-40 )