Relationship between Thyroid Ultrastructural and Functional Changes in Mice Pattern between Heat of Excess Type and Fever of Deficiency Type
XU Zhi-wei
CHEN Qun
Liu Ya-mei
LEI Wei-wei
WANG Bing
CHEN Zhi-xi
Abstract:Objective:To observe the connexion of the levels of thyroxine and ultrastructure of the thyroid gland and energy metabolism change of functional.Method:The levels of thyroxine(T3、T4、rT3)and thyroid stimulating hormone(TSH) in rat serum were measured by radioimmunoassay,and ultrastructure of the thyroid gland were examined by transmission electron microscopy(TEM)in mice pattern between heat of excess type and fever of deficiency type.Result:The results showed that the levels of T3 and T4 in serum significantly increased and the levels rT3 of decreased,the level of TSH being unchanged obviously in fever of deficiency type;the levels of T3、T4、rT3 and TSH did not increase obviously in heat of excess type.These evidences were almost in accord with the morphological changes of the thyroid follicular epithelial cell,in other words,the changes of ultrastructure of the thyroid follicular epithelial cell were more significant in fever of deficiency type than those in heat of excess type.Conclusion:The levels of thyroxine in mice pattern of Re syndrome are paralles with the changes of ultrastructure of the thyroid follicular epithelial cell.
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Publication Date:2001-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 23-26 )