Experimental Study On Effect of NaoluoTong In Prevention And Treatment of Cerebral Ischemic Injury
Abstract:Objective: To study mechanism of NaoLuoTong on cerebral ischemicinjury. Method: Multifactorial animal model of the Qi-deficiency and blood-stasis type of cerebral ischemia was established to observe the effect of NaoLuoTong on the activity of t-PA (tissue plasminogen activator) and PAI(plasminogen activator inhibitor), the level of IL-1 β(interleukin-1 β) and IL-6(interleukin-6). Result: NaoLuoTong could remarkably increase the activity of t-PA(P<0.01),remarkably decrease the activity of PAI(P<0.01), decrease the level of IL-1 β(P<0.01) and IL-6(P<0.05). Conclusion: NaoluoTong could improve the fibrinolytic system, reduce the excess production of inflammatory media, therefore provided a further evidence for its protective effect on ischemic cerebral injury
Keywords:NaoLuoTongcerebral ischemiat-PAPAIIL-1 βIL-6
Publication Date:2001-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 26-29 )
