Experimental study on K562 cells and hematopietic stemcells with Fuzheng-Quxie Tablet
Abstract：Objective:To study the mechanism of Fuzheng Quxie Tablet (FZQXD) in treating myelodysplastic syndromes (MDS).Methods: The in vitro effect of FZQXD on K562 cell line and hematopietic stem cells were studied with flow cytometery and cell cultuer.Results:FZQXD inhibited P53 protein expression,markedly promoted the proliferation of colony forming unit-erythrocytes(CFU-E).no effect on K562 cell in inducing apoptosis and cell-cycle.Conclusions:That FZQXD slightly inhibited P53 protein expression and markedly promoted the proliferation of colony forming unit-erythrocytes (CFU-E) might be one of the mechanisms in treating myelodysplastic syndromes.
Machine-generated Keywords：
Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 27-29 )