Biological Agents in the Treatment of Skin Diseases and Fungal Infections, Fungal Microbiota Imbalance
Abstract：The application of biological agents in the treatment of skin diseases is becoming increasingly widespread. They work by targeting and blocking key cells, cytokines, and their pathways, thereby reducing inflammatory responses and treating related diseases such as psoriasis and atopic dermatitis. However, this treatment, while anti-inflammatory, also reduces the body's defense against microorganisms, disrupting the immune balance between the host and the microbiota, thus leading to infections. This article reviews clinical reports on fungal infections or fungal microbiota disturbances that occur during the use of commonly applied biological agents in dermatology, aiming to provide a basis for the standardized management of biological agents in the treatment of skin diseases.
Keywords：Biological AgentsFungal InfectionIL-17
Publication Date：2025-10-28
Online Publishing Date：2025-11-19(First online date of this platform, not the publication date of the document)
Pages：5( 547-551 )