Fungal distribution and resistance in elderly invasive pulmonary fungal infection patients'bronchoalveolar lavage fluid
WANG Kangchun
WANG Nan
LI Ran
Abstract：Objective To investigate fungal distribution and drug resistance of fungi isolated from elderly invasive pulmonary fungal infection(IPFI)patients'bronchoalveolar lavage fluid,thereby providing a guide for clinical management and infection prevention.Methods Retrospective analysis of fungal culture and drug susceptibility data from bronchoalveo-lar lavage fluid samples(from January 2022 to December 2024)was performed.Results There were 155 fungal isolates i-dentified.C.albicans was predominated(47.7%),followed by C.tropicalis(17.4%),Aspergillus spp.(11.0%)and C.glabrata(10.3%).Multidrug-resistantC.auris accounted for 5.8%.Non-auris Candida showed>95.9%suscepti-bility to(AMB)and 5-fluorocytosine.Conclusion C.albicans remains primary pathogen.Susceptibility testing-guided therapy and strengthened infection control are crucial for elderly IPFI patients.
Keywords：invasive pulmonary fungal infectionbronchoalveolar lavage fluidfungiresistance
Publication Date：2025-10-28
Online Publishing Date：2025-11-19(First online date of this platform, not the publication date of the document)
Pages：4( 494-497 )