Distribution of 1118 cases of superficial fungal culture-positive strains and antifungal susceptibility analysis of yeasts
DENG Liuying
ZHENG Wenai
TANG Xiaozheng
YAN Weichen
Abstract：Objective To analyze the distribution of pathogenic fungi in superficial fungal infections in Hainan Province and the drug susceptibility characteristics of yeasts,providing a basis for clinical diagnosis and treatment.Methods A retrospec-tive analysis was conducted on 1118 cases of positive fungal cultures from the dermatology department of the Fifth People's Hospital of Hainan Province from January 2018 to December 2023,focusing on the distribution of fungal species,infection sites,and yeast drug susceptibility results.Results The majority of the 1118 strains were derived from onychomycosis pa-tients(75.49%),followed by tinea corporis(8.32%)and tinea pedis(7.07%).Among them,yeasts and yeast-like fungi accounted for 57.6%(644 cases),with Candida parapsilosis(18.41%)being the most common,often found in nail speci-mens;dermatophytes accounted for 27.01%(302 cases),with Trichophyton rubrum(17.62%)being the most prevalent,commonly found in toenail specimens.The drug susceptibility results showed that Candida glabrata and Candida dublini-ensis had susceptibility rates>90%to most drugs,while Candida albicans had a susceptibility rate of only 36.0%to itra-conazole,and Candida tropicalis showed low susceptibility rates to five drugs.Conclusion The fungal culture specimens in this hospital are primarily derived from nail specimens,leading to significant differences in species distribution compared to reports from other regions.The susceptibility of yeasts to antifungals varies by species and requires continuous monitoring.
Keywords：superficial mycosisfungal cultureyeastsusceptibility testing
Publication Date：2025-08-28
Online Publishing Date：2025-09-04(First online date of this platform, not the publication date of the document)
Pages：7( 424-430 )