A case of Pneumocystis jirovecii complicated with herpesvirus following renal transplantation and literature review
LI Zebin
LUO Xinyu
LIN Jin
LI Nian
BEI Rongrong
HU Jiahan
Abstract：To investigate the clinical manifestations,diagnosis,and treatment of Pneumocystis jirovecii(PJ)complicated by human herpesvirus 5(HHV-5)infection following kidney transplantation,relevant literature alongside domestic and in-ternational reports.A 53-year-old male patient was admitted to the hospital with a fever lasting one day,one year post-kid-ney transplantation.CT scan of the lungs revealed multiple ground-glass opacities in both lungs indicative of pulmonary in-fection,potentially viral and/or fungal infection.Peripheral blood DNA testing confirmed the presence of PJ and HHV-5.of immunosuppressants,continuous high-flow oxygen therapy,meropenemTMP-SMX caspofunginvoriconazole ganciclovir,as well as enhance immunity.Following these interventions,the patient's symptoms improved significantly.Currently,there are few reported cases of renal transplantation complicated by PJ and HHV-5 in clinical settings.Diagnosis primarily relies on DNA detection;however,the slow turnaround time for test results can delay necessary treatment interventions for this con-dition.
Keywords：after kidney transplantationPneumocystis jiroveciiHHV-5pulmonary infection
Publication Date：2025-06-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 280-283,317 )