Clinical feature and pathogen analysis of 285 cases of fungal rhinosinusitis
ZOU Liufeng
ZHU Yajing
ZHENG Yiyang
KANG Yuanchun
XIE Kaipeng
WU Xiaoqin
PENG Hu
LIAO Jianchun
Abstract：Objective To explore the clinical feature and pathogens of chronic fungal rhinosinusitis through a multicenter retrospective study,in order to deepen clinical understanding of chronic fungal rhinosinusitis.Methods A systematic analy-sis was conducted on the clinical manifestations,pathogenic analysis,imaging anatomy,pathological examination,and treat-ment methods of 285 cases of chronic fungal rhinosinusitis admitted to the Second Affiliated Hospital of Naval Medical Uni-versity,the Second Hospital of Zhangzhou,and the 909 Hospital of the People's Liberation Army Joint Service from January 2008 to January 2018.Results Among the 285 patients,the main clinical characteristics were rhinobyon(50.18%),head-ache(40.70%),and runny nose(16.49%),with the majority of cases occurring in the unilateral maxillary sinus(67.37%).The imaging features were irregular nodular or polyp like hyperplasia of soft tissue in the nasal cavity and sinuses,with more punctate or patchy high-density calcification on top,and invasive lesions with visible bone destruction.The sur-gery was the main treatment for chronic fungal sinusitis.All 285 patients underwent endoscopic sinus surgery without any serious complications during or after the operations.Pathogenic testing revealed 241 cases(84.56%)of Aspergillus infec-tion and 22 cases(7.71%)of Mucor infection.Conclusion Chronic fungal rhinosinusitis is a chronic rhinosinusitis with typ-ical imaging manifestations,mostly unilateral maxillary sinus pathogenesis due to Aspergillus infection.Endoscopic surgery is safe and effective in the treatment of fungal maxillary sinusitis.
Keywords：chronic fungal rhinosinusitisclinical featurepathogenic fungi
Publication Date：2023-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 507-510 )