The effects of NLRP3 inflammasome in fungal infection
XU Zhi-qing
WU Da-qiang
SHAO Jing
WANG Tian-ming
WANG Chang-zhong
Abstract：In fungal infection,host immune cells recognized pathogen associated molecular patterns (PAMPs),such as beta glucan,by pattern recognition receptors (PRRs) and trigger innate immunity against fungi.NLRP3,a member of NLR family,together with ASC and caspase-1,constituting NLRP3 inflammasome,participated in or controls fungal infection.In this paper,we reviewed the role of NLRP3 inflammasome in the fungal infection in recent years.
Keywords：Candida albicansNLRP3 inflammasomeinnate immunitypattern recognition receptors (PRRs)pathogen associated molecular patterns (PAMPs)
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 162-167 )