Evaluation of efficacy and safety of 1％ luliconazole cream in the treatment of tinea corporis and tinea cruris
ZHU Min
SU Hui-lin
LI Li
CHENG Ben-lin
ZHU Jun-hao
ZHANG Qiang-qiang
Abstract：Objective To evaluate the efficacy and safety of 1％ luliconazole cream in the treatment of tinea corporis and tinea cruris.Methods A single-center,single-blind,randomized,positive drug (1％ terbinafine hydrochloride cream) controlled trial was conducted.Both 1％ luliconazole cream and 1％ terbinafine hydrochloride cream were applied once daily for 2 weeks to the rashes.Patients were evaluated at 0 (baseline),1,2 and 4 weeks.Results Thirty cases in the trial group and 28 cases in the control group were evaluated.The effective rate at 1 week was 43.33％ in the trial group and 28.57％ in the control group (P＞0.05);96.67％ versus 85.71％ at 2 weeks and 96.67％ versus 100.00％ at 4 weeks respectively (P＞0.05).Mycological cure rates at 1 week both were 50％ in the trial group and control group;96.67％ versus 85.71％ at 2 weeks and 96.67％ versus 100.00％ at 4 weeks respectively (P＞0.05).Treatment-related adverse events were not seen in this study.Conclusion This study suggests that 1％ luliconazole cream was effective and safe in the treatment of tinea corporis and tinea cruris.
Keywords：luliconazoleterbinafinetinea corporistinea cruris
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 42-44 )