The effects of tetrandrine on Candida albicans biofilm and germ tube formation
GUO Lan?fang
LIU Da?biao
ZHOU Meng?jie
HUA Teng?jiang
Abstract：Objective To study the effects of tetrandrine ( Tet) on Candida albicans biofilm and germ tube formation. Methods Using the XTT method to observe the effect of Tet on C.albicans biofilm.0.01,0.1,1μmol/L of Tet and C.albicans suspensions were incubated together,then the rates of bud tube were counted.The experiment was repeated 5 times.Results Tet had obvious inhibitory effects on C.albicans biofilm and the germ tube (P<0.05).The biofilm and germ tube formation inhibition rate was the highest in 1μmol/L of Tet,compared with the negative control group (P<0.05) and the 0.01,0.1μmol/L groups (P<0.05).Conclusions Tet had inhibitory effect on C.albicans biofilm and germ tube formation.
Keywords：tetrandrineCandida albicansgerm tubebiofilm
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 276-278 )