Dendritic cells in anti-fungal immunity
WANG Ruili
LIAO Yong
AO Junhong
Abstract：The number of life?threatening fungal infections has skyrocketed recently as a result of the abused of antibiotics,chem?otherapy drugs and immunosuppressive drugs,as well as the increased immunocompromised patients.Dendritic cells(DCs)are the most powerful antigen?presenting cells.As the bridge between the innate and adaptive immune system,DCs play a central role in rec?ognizing a variety of pathogens and presenting antigens. Many investigations demonstrate that DCs can effectively recognize fungal pathogens through several receptors on the cellular surface and promote the immune responses against invasive fungi.Here,we de?scribe the characteristics of the various DCs subsets,the way of DC recognizing fungi,and their functions in immunity against fungal pathogens.
Keywords：dendritic cellsfungal infectionimmune response
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 39-43,21 )