An analysis of evaluating the texture of pituitary adenoma and the effect of neuroendoscopic resection based on diffusion-weighted imaging
YU Yi
FENG Bao
XIA Hao
WU Junyi
ZHU Yufu
Abstract：Objective To investigate the value of diffusion-weighted imaging(DWI)in assessing the texture of pituitary adenoma(PA)and predicting the extent of neuroendoscopic.resection.Methods A retrospective analysis was conducted on 231 patients with PA,including general clinical data(age,gender,symptoms,etc.),pathological data(tumor texture,collagen content),and imaging data(tumor size,ADC ratio,etc.)in the Affiliated Hospital of Xuzhou Medical University from January 2020 to December 2022.Patients were divided into soft group and hard group according to intraoperative pathological results,and the ability of DWI to predict tumor texture was evaluated.According to the postoperative reexamination imaging results,the application value of DWI in the degree of tumor resection was discussed.Correlation analysis and multiple linear regression were used to analyze the relationship between ADC ratio and tumor texture and collagen content,with ROC curves for validating its diagnostic efficacy.Logistic regression was applied to analyze the relevant factors influencing tumor resection under neuroendoscopy.Results All patients underwent neuroendoscopic transsphenoidal surgery for pituitary adenoma.All patients underwent neuroendoscopic transsphenoidal resection for pituitary adenoma.There were differences in collagen content,ADC ratio,and degree of tumor resection between the soft and hard groups.Multiple linear regression analysis showed that the effects of collagen content and tumor texture on ADC ratio were statistically significant.Spearman's correlation analysis showed that there was a correlation between ADC ratio and tumor texture and collagen content,and collagen content was also significantly correlated with tumor texture.Univariate regression analysis showed that tumor volume,tumor size,tumor texture,ADC ratio,collagen content,and tumor invasiveness were the influencing factors of total tumor resection.Multivariate regression analysis showed that tumor size and ADC ratio were independent influencing factors for total tumor resection.Conclusions The application of DWI before neuroendoscopic transsphenoidal pituitary adenoma resection can effectively assess the tumor texture and provide important reference information for surgery,thereby reducing the risk of excessive traction and pituitary injury during surgery,and improving the tumor resection rate.
Keywords：Pituitary adenomaDiffusion-weighted imagingNeuroendoscopyTumor consistency
Publication Date：2025-08-20
Online Publishing Date：2025-09-15(First online date of this platform, not the publication date of the document)
Pages：6( 396-400,408 )