N6-Methyladenosine modifications in the regulation of long non-coding RNAs and its role in tumor progression
LIU Jinfang
TANG Jian
LI Chujun
YAO Gang
LUO Binlin
Abstract：N6-methyladenosine(m6A)methylation modulates RNA functions through regulating various mechanisms such as splicing,stability,translocation,and translation.Reversible m6A modifications can also regulate the expression and function of long non-coding RNAs(lncRNAs),thereby influencing tumor cell proliferation,migration,and apoptosis,and plays an important role in the development of tumors.This article explores the regulatory effects of m6A methylation on lncRNAs and its mechanisms and impacts on the progression of malignant tumors.
Keywords：RNA methylation modificationN6-methyladenosineLong non-coding RNAMalignant tumors
Publication Date：2025-04-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 202-208 )