Overview of tumor vaccines and advances in breast cancer vaccine research
LIAO Ning
REN Yongqi
DENG Shuxuan
HE Yan
WEN Xingxuan
LI Yingxue
ZHANG Peiting
LI Zhuohui
CAO Li
Abstract：Breast cancer is one of the most common malignant tumors in women,and its high incidence and mortality pose a serious threat to global public health.Although the development of early screening and targeted therapies has improved breast cancer survival rates to some extent,reducing recurrence and metastasis remains a major challenge in treatment.In recent years,immunotherapy,especially cancer vaccines,has emerged as a potentially effective method to reduce breast cancer recurrence and mortality.Cancer vaccines aim to induce long-lasting,specific immune responses to eliminate tumor cells.Currently,breast cancer vaccines are gradually showing potential in the treatment of breast cancer.However,challenges such as the immunogenicity of the vaccine and optimization of dosing regimens remain obstacles to its clinical application.This review summarizes the basics and advance of breast cancer vaccines,discusses their main targets,types of vaccines,and related clinical research,and addresses the future directions for development.
Keywords：Breast cancerCancer vaccineImmunotherapyAnonymous antigens
Publication Date：2025-02-19
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：11( 5-15 )