Application of 18F-FDG PET-MRI and breast-specific PET in the clinical diagnosis and treatment of breast cancer
JIANG Linhong
DING Ziteng
WANG Dandan
CHEN Xiu
HOU Junchen
ZHANG Qian
ZHANG Jian
ZHANG Heda
Abstract：Objective To explore the application value of 18F-FDG PET-MRI and breast-specific PET in breast cancer diagnosis.Methods An analysis was conducted on the preoperative data of eight breast cancer patients who underwent 18F-FDG PET-MRI examinations.Among them,four patients also received breast-specific PET scans preoperatively.The imaging characteristics were assessed,the maximum uptake of the lesions was measured,and these findings were compared with the pathological results.Results The postoperative pathology confirmed breast cancer in all eight patients,consistent with the preoperative diagnosis.Among them,two were Stage Ⅳ,two were Stage ⅢB,three were Stage ⅡB,and one was Stage ⅠA.The average maximum diameter of the primary tumor was 8.6 cm,with an average SUVmax value of 13.05±8.77 for the breast lesions and an average SUVmax value of 9.56±8.10 for the axillary lymph nodes.Conclusions 18F-FDG PET-MRI can accurately show the morphology,boundary,density and tumor uptake of breast masses and lymph nodes,and breast-specific PET can precisely measure the volume of the tumor,demonstrateing signicifant clinical application value for preoperative evaluation and treatment of breast cancer.
Keywords：18F-FDG PET-MRIBreast-specific PETBreast cancerNeoadjuvant therapy
Publication Date：2024-12-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 560-565 )