Analysis of influencing factors of esophageal cancer and precancerous lesions in rural residents of Jiangsu province
LIU Fudong
WU Lingling
MIAO Weigang
HAN Renqiang
SU Jian
ZHOU Jinyi
LUO Pengfei
Abstract：Objective To investigate the detection and influencing factors of esophageal cancer and precancerous lesions in the rural areas of Jiangsu province,and provide theoretical basis for esophageal cancer prevention.Methods The permanent residents aged 40-69 years old who participated in the Early diagnosis and early treatment of upper digestive tract cancer in rural areas of Jiangsu province program from January 2017 to December 2022 were selected.A total of 51,198 residents aged 40-69 years old were selected as the research subjects.Risk factors questionnaire,endoscopy,and tissue biopsy were carried out to determine the precancerous lesions or esophageal cancer according to the pathological diagnosis.SPSS 22.0 software was used for chi-square test.Multinomial logistic regression was used to analyze the influencing factors of esophageal precancerous lesions and esophageal cancer.Results 1,279 cases of precancerous lesions and 741 cases of esophageal cancer were detected in 51,198 subjects(2.50%and 1.45%,respectively).Multinomial logistic regression analysis showed that high school education level or above(OR= 0.81,95%CI:0.66～0.98),a household income of over 50,000 yuan(OR=0.82,95%CI:0.73～0.93),and eating fresh fruit once or twice a week(OR= 0.70,95%CI:0.52～0.93)were low risk factors of esophageal precancerous lesions;Male(OR=1.45,95%CI:1.27～1.65),age(OR=5.35,95%CI:4.22～6.79),eating pickled food(＜twice/week:OR= 1.80,95%CI:1.42～2.28;≥twice/week:OR= 3.01,95%CI:2.35～3.87),esophagitis(OR=1.65,95%CI:1.19～2.31)and geting angry during meals(OR=2.43,95%CI:2.07～2.85)were high risk factors of esophageal precancerous lesions;A household income of over 50 000 yuan was a low risk factor of esophageal cancer(OR=0.74,95%CI:0.64～0.86),male(OR=1.64,95%CI:1.38～1.95),age(OR=5.54,95%CI:4.11～7.46),eating moldy food once or twice a week(OR=1.87,95%CI:1.38～2.54),sophagitis(OR=1.86,95%CI:1.22～2.86),and getting angry during meals(OR=2.95,95%CI:2.37～3.67)were high risk factors of esophageal cancer.Conclusions The detection rate of esophageal cancer and precancerous lesions in rural areas of Jiangsu province is relatively high.Therefore,it is necessary to strengthen the promotion of esophageal cancer health knowledge among males,the elderly,people with a history of esophagitis and poor eating habits,so as to reduce the risk of esophageal cancer.
Keywords：Esophageal CancerPrecancerous LesionsRisk factorsMultinomial logistic regression analysis
Publication Date：2024-04-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 116-121 )