The rising of perioperative whole-course immunotherapy for resectable non-small cell lung cancer
CHEN Yue
LIU Ying
CAI Ruoxue
GUO Mengya
PENG Weiwei
SHA Huanhuan
FANG Ying
ZHOU Guoren
Abstract：Lung cancer is the leading cancer in mortality in the world,and its diagnosis and treatment progress have been concerned.In the early and middle stages,operable non-small cell lung cancer(NSCLC)has traditionally been treated with a combination of operations.With the advent of immune checkpoint inhibitors(ICIs),perioperative treatment of NSCLC has also changed.More and more studies have shown that"whole-course immunotherapy"may produce greater benefits,that is,"neoadjuvant chemotherapy combined with immunotherapy+surgery+immunoadjuvant therapy",commonly known as"sandwich cake"and"sandwich"treatment mode.This article reviews the origin and progress of perioperative whole-course immunotherapy for NSCLC,in order to provide a basis for the formulation of perioperative comprehensive treatment for lung cancer.
Keywords：Non-small cell lung cancerImmune checkpoint inhibitorsNeoadjuvant therapyPerioperative treatmentClinical research
Publication Date：2023-12-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：8( 591-598 )