Significance of retroperitioned lymph node excision in the treatment of ovarian endodermal sinus tumor
WU Yuzhong
QU Junwei
NI Jing
WANG Jinhua
Abstract：Objective To evaluate the impact of lymphadenectomy on the relapse and survival of ovarian endodermal sinus tumor. Methods The clinical data of 52 OYST cases treated in Jiangsu Cancer Hospital from Feb. 1996 to Mar. 2010 were analyzed retrospectively. According to surgical procedure,all cases were divided into two groups:research group with 22 cases received cytoreductive surgery plus retroperitoneal lymphadenecto-my,and control group with 30 cases did not receive retroperitoneal lymphadenectomy. The indexes of recurrence rate were compared between two groups and the independent factors related to relapse of disease were identified. Results There was no statistical difference in the recurrence rate and mean recurrence duration between two groups (P>0. 05). International Federation of Gynecology and Obstetrics (FIGO) staging,chemotherapy regi-men,and required chemotherapy courses that got the serum AFP levels back to normal were the significant fac-tors related to the relapse. Moreover,the presence of lymph node metastasis had no significant effect on relapse. Conclusion Lymphadenectomy may not bring benefitial effect for patients and standardized chemotherapy can improve the prognosis of patients with OYST.
Keywords：ovarian endodermal sinus tumorlymph node excisionchemotherapyrelapse
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 287-291 )