Analysis of two preoperative radiotherapy regimens in multimodality therapy of rectal carcinoma
ZHANG Zhongde
LI Hui
ZHI Hui
Abstract：Objective To investigate the clinical effect and adverse reaction of preoperative short-course and long-course radiotherapy in radical operation of rectal carcinoma. Methods Some patients staged as cT2-3 N0-2 M0 were randomly arranged into two group,short-course group received radiotherapy and surgery after 7~8 weeks,long-course group received radiotherapy and surgery after 4~6 weeks. Results The rate complete path-ological of response was 15. 1% for patients who received short-course radiotherapy and 15. 6% for patients who had long-course radiotherapy. There were no significant differences between two groups and there were similar wound infection, intra-abdominal infection, haemorrhage, anastomotic leak, wound dehiscence, mortality and recurrence rate 1 year after surgery in two groups. Conclusions The rate complete pathological of response, adverse reaction, mortality and recurrence 1 year after surgery in two groups were similar.
Keywords：rectal carcinomaneoadjuvant radiotherapyshort-course radiotherapylong-course ra-diotherapycolorectal cancer radical correction
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 93-95 )