Applied research of intra-operative biopsy during TURBT in the treatment of bladder cancer
LI Xiao-jun
Abstract：Objective To evaluate the value and significance of intra-operative biopsy from the bottom and the margin of the tumors during TURBT in the treatment of bladder cancer.Methods 58 patients underwent TURBT with urothelial carcinoma from Mar.2010 to Apr.2013.28 patients underwent biopsy,the biopsy parts include the bottom and the margin of the tumors mucousmembrane,the left 30 patients did not receive biopsy. The recurrence and progression rates were observed one year after TURBT.Results (1)In biopsy group,one case biopsy specimen displayed muscle-invasive bladder cancer,radical total cystectomy was executed accord-ingly.5 patients did routine Re-TURBT including 3 patients with no signs of muscle tissues observed and 2 pa-tients with epithelial dysplasia in biopsy,the rest biopsy specimens were normal.During a one-year follow-up for 28 patients,5 patients had recurrence one year after TURBT in biopsy group along with 2 cases of progres-sion.(2)In non-biopsy group,2 cases showed muscle-invasive bladder cancer,28 cases were non-muscle in-vasive bladder cancer.During a one-year follow-up for 30 patients,10 patients had recurrence along with 6 ca-ses of progression in non-biopsy group.Conclusion Intra-operative biopsy from the bottom and the margin of the tumors during TURBT is helpful to identify the clinical staging and pathologic tumor grading,improving the detection rate of residual tumors,identifying the resection scope and depth,and providing reference for Re-TURBT.
Keywords：bladder cancerTURBTbiopsy
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 353-355 )