Changes of intestinal permeability and toxicity effect in advanced gastric carcinoma induced by neoadju-vant chemotherapy through taking oral glutamine
LI Gang
XIA Lei
WEI Wei
ZHOU Bin
GU Rong-min
WEN Xu
MING Xuezhi
CHEN Huanqiu
Abstract：During treating wich NACT,compared with the ratio of L/Mof B group,the incidence of diarrhea,vomiting and nausea of A group was significantly lower.The L/Mratio of all patients increased after treating wich NACT,and the ratio of patients in B group was higher than that in A group.But no significant differences between two groups in pathologic response were observed in postoperative samples.Conclusions Oral glutamine could alle-viate NACT-induced increase in intestinal permeability and the toxicity,such as diarrhea,vomiting and nausea, but had no effect on the pathological response of gastric cancer.
Keywords：advanced gastric cancerneoadjuvant chemotherapyintestinal mucous permeabilitychemotherapy side effect response
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 341-344 )