Evaluation of metastatic nasopharyngeal carcinoma under the treatment of second-line chemotherapy of vinorelbine plus nedaplatin
SONG Haiping
WANG Hongbo
Abstract：Objective To observe the curative effect and adverse reaction of vinorelbine plus nedaplatin regimen for metastatic nasopharyngeal carcinoma. Methods 92 patients with metastatic nasopharyngeal carci-noma were chosen to accept second-line chemotherapy;they were given vinorelbine 25-30 mg/ m2 on day 1 and day 8 and nedaplatin 100 mg/ m2 on day 1 and day 8. Results The response rate was 54. 3% . The 1-year sur-vival rate reached 52. 2% ,and 2-year survival rate reached 12. 2% . The major toxic effects included marrow suppression,nausea and vomiting. Conclusions A reasonable efficacy and long survival time are shown in the second-line chemotherapy of vinorelbine plus nedaplatin for patients with metastatic nasopharyngeal carcinoma.
Keywords：nasopharyngeal carcinomametastaticvinorelbinenedaplatinsecond-line chemo-therapy
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 222-224 )