Assessment of the clinical effect of optimized percutaneous vertebroplasty in treatment of Kümmell's disease
LIU Tao
ZHI Zhongzheng
ZHOU Fuchao
ZHANG Rongcheng
PAN Weicheng
KANG Jian
MIAO Jinhao
HE Zhimin
Abstract：Objective To explore the clinical effect of optimized percutaneous vertebroplasty(PVP)in treatment of osteoporotic vertebral fracture nonunion(Kümmell's disease,KD).Methods A retrospective analysis was conducted on the clinical data of 153 patients with KD who underwent PVP in the Department of Spinal Surgery of Shanghai Fourth People's Hospital,Tongji University from January 2021 to January 2024.Among the patients,78 patients receiving conventional PVP were assigned to the control group,while the other 75 patients receiving optimized PVP(including cross-puncture,filling with gelatin sponge and artificial bone,bone cement trailing and vacuum intravertebral cleft freshness)were assigned to the observation group.The Visual Analogue Scale(VAS)scores for assessing low back pain and the Oswestry Disability Index(ODI),the vertebral body height of the injured vertebrae,the angles formed between the upper endplate and the lower endplate of the injured vertebrae,and the thoracolumbar Cobb angles were collected before the operation,and at 3 days,1 month,3 months,6 months and 12 months after the operation for comparative analysis.Results The VAS scores and ODI in the two groups at each time point after the operation were significantly lower than those before the operation(P＜0.05),but there were no significant defferences between the two groups(P＞0.05).The vertebral body height of the injured vertebrae,the angles formed between the upper endplate and the lower endplate of the injured vertebrae,and the thoracolumbar Cobb angles in the two groups at each time point after the operation were significantly improved compared with those before the operation(P＜0.05),and the improvement in the observation group was more significant(P＜0.05).The incidence of complications in the observation group was lower than that in the control group,with a statistically significant difference between the two groups(2.7％vs 25.6％;x2=16.392,P＜0.001).Conclusion The optimized PVP can enhance bone cement anchoring,restore and maintain the vertebral height of the injured vertebrae,and significantly alleviate back pain in the KD patients,improve their lumbar function and quality of life.
Keywords：OsteoporosisVertebral compression fracturePercutaneous vertebroplasty(PVP)Kümmell's disease(KD)
Publication Date：2026-02-28
Online Publishing Date：2026-03-31(First online date of this platform, not the publication date of the document)
Pages：6( 153-158 )