Analysis on the incidence and risk factors of complications after tubeless thymoma resection:a retrospective study of 80 cases

XU Yi; LU Ting; XU Ke; FENG Xiaoyan; XIONG Rongsheng

doi:10.3969/j.issn.1674-3806.2025.10.06

Abstract：Objective To explore the incidence and independent risk factors of complications after tubeless thymoma resection,and to provide a reference basis for the clinical optimization of perioperative management.Methods A retrospective analysis was conducted on the clinical data of 80 patients who underwent tubeless thymoma resection in Nanxishan Hospital of Guangxi Zhuang Autonomous Region from January 2021 to July 2025.The patients'general data,surgical-related indicators and postoperative complications were recorded.Univariate analysis was used to screen for the risk factors,and multivariate Firth-corrected logistic regression was used to analyze the independent risk factors.Results In the 80 patients,11 patients had postoperative complications,among which arrhythmia and incision fat liquefaction were the most common.Univariate analysis showed that the maximum diameter of tumors,Masaoka-Koga stage,myasthenia gravis,surgical method,duration of operation,intraoperative blood loss and duration of artificial pneumothorax were associated with the occurrence of complications(P＜0.05).The analysis results of multivariate Firth-corrected logistic regression indicated that the longer maximum diameter of tumors,longer duration of operation and longer duration of artificial pneumothorax were independent risk factors for the occurrence of postoperative complications after tubeless thymoma resection(P＜0.05).Conclusion Tubeless thymoma resection is generally safe and feasible,but patients with longer maximum diameter of tumors,longer duration of operation and longer duration of artificial pneumothorax have a higher risk of complications.For the high-risk patients,preoperative assessment and perioperative management should be strengthened to reduce the incidence of postoperative complications.