Observation on clinical efficacy of transumbilical single-incision plus one-port laparoscopy with VICRYL baseball suture technique in treating giant uterine fibroids with a diameter ≥10 cm

ZHAO Yanhong; GAO Jianhong; XU Donglei; SUN Peipei; ZHANG Jing

doi:10.3969/j.issn.1674-3806.2025.09.15

Abstract：Objective To observe the clinical efficacy of transumbilical single-incision plus one-port laparoscopy with VICRYL baseball suture technique in treating giant uterine fibroids with a diameter ≥ 10 cm.Methods A retrospective analysis was conducted on the clinical data of the patients with giant uterine fibroids who were admitted to the People's Hospital of Langfang City from September 2021 to June 2023.In the patients,52 patients who received the treatment of transumbilical single-incision plus one-port laparoscopy with VICRYL baseball suture technique were selected as observation group,while other 52 patients who received conventional four-port laparoscopic surgery by using a matching method at a ratio of 1∶1 were selected as control group.The perioperative indicators,postoperative Visual Analogue Scale(VAS)scores,trauma stress indicators[superoxide dismutase(SOD),reactive oxygen species(ROS),C-reactive protein(CRP),glutathione peroxidase(GSH-Px)],patient subjective satisfaction with surgical incision and the occurrence of complications were compared between the two groups.Results The duration of operation in the observation group was shorter than that in the control group,and time to first anal exhaust and time to first ambulation after operation in the observation group was earlier than that in the control group,with statistically significant differences(P＜0.05).There were no statistically significant differences in intraoperative blood loss and hospital stay between the two groups(P＞0.05).The VAS scores at 6 hours,9 hours,12 hours,24 hours and 32 hours after operation in the observation group were significantly lower than those in the control group(P＜0.05).On the first and third days after operation,the levels of CRP and ROS in the observation group were lower than those in the control group,while the levels of GSH-Px and SOD in the observation group were higher than those in the control group,with statistically significant differences(P＜0.05).The rate of patient subjective satisfaction with surgical incision in the observation group was significantly higher than that in the control group(98.08％vs 75.00％;x2=11.886,P=0.001).There was no statistically significant difference in the incidence of complications between the two groups(3.85％vs 1.92％;x2=0.000,P=1.000).Conclusion The transumbilical single-incision plus one-port laparoscopy with VICRYL baseball suture technique is a safe and feasible treatment for giant uterine fibroids with a diameter ≥10 cm,with good patient subjective satisfaction with surgical incision,and benefits for early postoperative recovery of the patients.