Analysis on imaging features of central and peripheral intraductal papillomas on cone-beam breast CT
FENG Xianmei
ZHAO Xin
WEI Wei
HUANG Lei
ZHENG Zhongtao
Abstract：Objective To investigate the differences in the imaging features of cone-beam breast computed tomography(CBBCT)between central intraductal papilloma(IDP)and peripheral IDP,and to evaluate the application value of CBBCT in preoperative differential diagnosis.Methods A retrospective analysis was conducted on the clinical and imaging data of 96 patients who underwent CBBCT in Guangxi Medical University Cancer Hospital from July 2019 to December 2023 and whose surgical specimens were pathologically confirmed as IDP.Among these patients,there were 57 patients in central IDP group and 39 patients in peripheral IDP group.The CBBCT imaging features and related measurement indicators of the lesions were analyzed and compared between the two groups.Results Compared with the peripheral IDP group,the central IDP group had shorter distance from the anterior edge of the lesion to the base of the nipple[(1.12±1.03)cm vs(3.83±1.87)cm,P＜0.05],and higher proportion of the long axis of the lesions following the same course as the mammary duct(84.21％vs 51.28％,P＜0.05),and higher standardized CT values of each stage in plain CT scan and enhanced CT scan(P＜0.05).There were no significant differences in the maximum diameter of the lesions,enhancement types,duct dilatation,vascular signs around the lesions,precontrast CT density,enhancement rate and time-density curve(TDC)types between the two groups(P＞0.05).Both groups were mainly characterized by smooth edges,round or oval shapes,and uniformly enhanced mass-like enhancement of the lesions,while TDC was mainly platform-like.Conclusion There are certain differences in CBBCT imaging features between central IDP and peripheral IDP,especially in the location of the lesion(distance from the base of the nipple),morphology of the lesion(the long axis following the same course as the mammary duct)and enhanced degree(standardized CT values).These features are helpful for the preoperative classification and diagnosis of IDP.
Keywords：Intraductal papilloma(IDP)Cone-beam breast computed tomography(CBBCT)Imaging featuresBreast tumor
Publication Date：2025-09-30
Online Publishing Date：2025-10-24(First online date of this platform, not the publication date of the document)
Pages：5( 982-986 )