Effects of FOCUS program on coping styles,family resilience and quality of life in acute leukemia patients and their primary family caregivers

MU Hezi; LIU Qin; CUI Yi; CHEN Changchang; ZHANG Yinling

doi:10.3969/j.issn.1674-3806.2025.08.19

Abstract：Objective To analyze the effects of FOCUS[family involvement(F),optimistic attitude(O),coping effectiveness(C),uncertainty reduction(U)and symptom management(S)]program on coping styles,family resilience and quality of life in acute leukemia(AL)patients and their primary family caregivers.Methods Sixty-four patients with AL who were admitted to Tangdu Hospital,Air Force Medical University from July 2023 to December 2023 and their primary family caregivers were recruited as research subjects.The patients and their primary family caregivers were divided into intervention group and control group by using random number table method,with 32 cases in each group.The control group received routine care+follow-up,while the intervention group received routine care+FOCUS program+follow-up.The intervention period was 12 weeks.Questionnaires were conducted on the patients and their primary family caregivers respectively before intervention(T0),4 weeks after intervention(T,),and 12 weeks after intervention(T2).The changes in coping styles,family resilience,and quality of life in the AL patients and their primary family caregivers were compared between the two groups before and after intervention.Results In the intervention group,2 patients had deteriorated conditions,and 1 patient withdrew voluntarily,and 2 patients were lost to follow-up,and finally 27 patients were included.In the control group,2 patients withdrew voluntarily,and 4 patients were lost to follow-up,and finally 26 patients were included.In the patients of the intervention group,Family Hardiness Index(FHI)scale scores and the positive coping scores in Trait Coping Style Questionnaire(TCSQ)at T,and T2 time points were higher than those at T0 time point,and the negative coping score in TCSQ at T,and T2 time points were lower than those at T0 time point,and the differences were statistically significant(P＜0.05).The Functional Assessment of Cancer Therapy-Leukemia(FACT-Leu)scale scores and FHI scores at T1 and T2 time points in the patients of the intervention group were higher than those in the patients of the control group,while the negative coping score in TCSQ at T,and T2 time points in the patients of the intervention group were lower than those in the patients of the control group,with statistically significant differences between the two groups(P＜0.05).In the primary family caregivers of the intervention group,FHI scale scores and the positive coping scores in TCSQ at T1 and T2 time points were higher than those at T0 time point,and the negative coping scores in TCSQ at T,and T2 time points were lower than those at T0 time point and in the primary family caregivers of the control group,FHI scale scores at T,and T2 time points were higher than those at T0 time point,and the differences were statistically significant(P＜0.05).The 12-Item Short-Form(SF-12)scores,FHI scores,and the positive coping scores in TCSQ at T,and T2 time points in the primary family caregivers of the intervention group were higher than those in the primary family caregivers of the control group,while the negative coping scores in TCSQ at T,and T2 time points in the primary family caregivers of the intervention group were lower than those in the primary family caregivers of the control group,with statistically significant differences between the two groups(P＜0.05).Conclusion The FOCUS program can effectively promote positive coping responses,reduce negative coping responses,enhance family resilience,and improve quality of life in both AL patients and their primary family caregivers.