Analysis on therapeutic effect of repetitive transcranial magnetic stimulation combined with conventional speech rehabilitation training on post-stroke dysarthria patients

FANG Chenjun; WANG Zhenni; ZHANG Weiming; XIAO Zihao; GAO Yi; SHEN Qin; ZHAO Na

doi:10.3969/j.issn.1674-3806.2025.07.18

Abstract：Objective To analyze the therapeutic effect of repetitive transcranial magnetic stimulation(rTMS)combined with conventional speech rehabilitation training on post-stroke dysarthria patients.Methods A total of 126 patients with post-stroke dysarthria who were admitted to Ruijin Hospital,Shanghai Jiao Tong University School of Medicine from June 2022 to March 2024 were recruited.The patients were divided into observation group and control group by using random number table method,with 63 patients in each group.The control group was given conventional speech rehabilitation training,while the observation group was given rTMS combined with conventional speech rehabilitation training.Both groups were treated continuously for 4 weeks.The total effective rates were compared between the two groups and the changes in articulating function,acoustic indicators and daily living ability were compared between the two groups before and after treatment.The occurrence of adverse reactions during the treatment period was recorded in both groups.Results The total effective rate of the observation group was significantly higher than that of the control group(P＜0.05).After treatment,the scores of the dimensions of reflex,breathing,lip movement,tongue movement,jaw movement,soft palate movement,laryngeal control and speech comprehension,and the total scores in the modified Frenchay Dysarthria Assessment Scale in both groups were higher than those before treatment,and the scores in the observation group were higher than those in the control group after treatment,and the differences were statistically significant(P＜0.05).After treatment,the voice loudness,clarity of articulations and modified Barthel Index scores in the two groups were higher than those before treatment,and these indicators in the observation group were higher than those in the control group after treatment,and the longest sound duration in the two groups was longer than that before treatment,and the longest sound duration in the observation group was longer than that in the control group after treatment,with statistically significant differences(P＜0.05).During the treatment period,neither group experienced any adverse reactions.Conclusion The combination of rTMS and conventional speech rehabilitation training is significantly effective in treatment of patients with post-stroke dysarthria.The combined treatment can effectively improve dysarthria,prolong the longest sound duration,and improve voice loudness,clarity of articulations and daily living ability.