Clinical analysis of 8 kidney disease pediatric patients complicated with posterior reversible encephalopathy syndrome

YANG Qin; FENG Shipin

doi:10.3969/j.issn.1674-3806.2025.06.16

Abstract：Objective To analyze the clinical features of kidney disease pediatric patients complicated with posterior reversible encephalopathy syndrome(PRES).Methods The clinical data of 8 kidney disease pediatric patients complicated with PRES who were admitted to the Affiliated Women's and Children's Hospital,School of Medicine,University of Electronic Science and Technology of China from August 2017 to August 2024 were retrospectively analyzed.The clinical manifestations,auxiliary examination results,treatment and prognosis of the pediatric patients were summarized.Results Glucocorticoids had been used in 8 pediatric patients,and immunosuppressants had been used in 7 pediatric patients.The main clinical manifestations of the pediatric patients were hypertension,headache,dizziness,convulsions,consciousness disorders and visual disturbances.Cranial magnetic resonance imaging(MRI)showed that the lesions mainly involved the parieto-occipital cortex and subcortex(7 cases),and possibly involved the frontal lobe(5 cases),temporal lobe(2 cases),semioval cent er(2 cases),and bilateral ventricles(1 case).After symptomatic treatment,both the clinical manifestations and MRI examination results of the pediatric patients improved.As of December 2024,there were no relapses of PRES in the 8 pediatric patients during the follow-up period.Conclusion The kidney disease pediatric patients can be complicated with PRES.The complicated PRES is associated with primary diseases,hypertension,and use of glucocorticoids and immunosuppressants to a certain extent in the kidney disease pediatric patients.Cranial MRI examination is helpful for early diagnosis.Timely and reasonable treatment can minimize the damage to the nervous system.