Observation on therapeutic effect of transurethral 1 470-nm wavelength laser prostatectomy with small-piece removal without morcellation in a tissue pulverizer for treatment of high-risk benign prostatic hyperplasia

LI Xiangping; TAO Yingxu; DENG Jiwang; LI Guobang; ZHONG Ruijuan; WEN Xingqiao

doi:10.3969/j.issn.1674-3806.2025.05.10

Abstract：Objective To observe the therapeutic effect of transurethral 1 470-nm wavelength laser prostatectomy with small-piece removal without morcellation in a tissue pulverizer for treatment of high-risk benign prostatic hyperplasia(BPH).Methods The clinical data of 100 patients with high-risk BPH who were admitted to Guangdong Provincial People's Hospital from July 2023 to July 2024 were retrospectively analyzed.The patients were divided into observation group(receiving transurethral 1 470-nm wavelength laser prostatectomy with small-piece removal without morcellation in a tissue pulverizer,50 cases)and control group(receiving transurethral 1 470-nm wavelength laser enucleation of the prostate in collocation with a tissue pulverizer,50 cases)according to different surgical methods.The surgical-related indicators,postoperative recovery,International Prostate Symptom Scores(IPSS)and quality of life(QOL)scores before surgery and 3 months after surgery,and the incidence of complications within 3 months after surgery were compared between the two groups.Results The operation time in the observation group was shorter than that in the control group,and the amount of intraoperative flushing fluid used in the observation group was less than that used in the control group,with statistically significant differences between the two groups(P＜0.05).However,there was no statistically significant difference in the decrease in hemoglobin levels between the two groups on the first day after surgery(P＞0.05).There was no statistically significant difference in the postoperative flushing time and indwelling time of the urinary catheter between the two groups(P＞0.05).The IPSS and QOL scores in both groups 3 months after surgery were lower than those before surgery,and the differences were statistically significant(P＜0.05).However,there were no significant differences in IPSS and QOL scores between the two groups before surgery and 3 months after surgery(P＞0.05).No complications occurred in the observation group.One case of urethral stricture occurred in the control group(2.00％).There was no significant difference in the incidence of complications between the two groups(x2=0.126,P=0.277).Conclusion The transurethral 1 470-nm wavelength laser prostatectomy with small-piece removal without morcellation in a tissue pulverizer is effective and safe in treatment of high-risk BPH,and can simplify the surgical process and effectively shorten the surgical time.