Analysis on characteristics of newly reported young HIV/AIDS patients in Hunan Province from 2016 to 2024

CHEN Jie; ZHOU Yanjun; QIN Biyun; ZHANG Jinghang; LIU Wei; ZHENG Jun; ZOU Xiaobai

doi:10.3969/j.issn.1674-3806.2025.04.02

Abstract：Objective To analyze the characteristics of newly reported young human immunodeficiency virus(HIV)/acquired immunodeficiency syndrome(AIDS)patients in Hunan Province from 2016 to 2024,and to provide reference basis for improving the quality of prevention and treatment of young AIDS patients.Methods The information of newly reported young HIV/AIDS patients in Hunan Province from 2016 to 2024 was collected through the HIV/AIDS Comprehensive Response Information Management System and was analyzed to explore the factors influencing the late diagnosis of HIV/AIDS and the timeliness of CD4+T lymphocyte testing.Results From 2016 to 2024,6 392 young HIV/AIDS patients were newly reported in Hunan Province,among whom 5 996 patients(93.80％)were male,and 4 282 patients(66.99％)were infected through same-sex sexual transmission,and 1 959 patients(30.65％)were infected through heterosexual sexual transmission,and 1 849 patients(28.93％)were students.The student patients were mainly 18-21 years old,and the proportion of male patients,unmarried patients,patients infected through same-sex sexual transmission and patients infected through non-marital and non-commercial sexual behaviors and patients receiving testing and counseling in the students was higher than that in the non-students(P＜0.05).Late diagnosis of HIV/AIDS was found in 1 108 cases(17.33％)and the first CD4+T lymphocyte test was completed in a timely manner in 4 429 cases(69.29％).The results of multivariate logistic regression analysis showed that the patients aged 22-24 years[OR(95％CI)=1.355(1.032-1.778)]were more likely to be late diagnosis of HIV/AIDS than those aged 15-17 years,and student patients[OR(95％CI)=0.774(0.654-0.917)],patients infected through same-sex sexual transmission[OR(95％CI)=0.831(0.719-0.961)],patients receiving testing and counseling[OR(95％CI)=0.492(0.426-0.567)]and patients from other sample sources[OR(95％CI)=0.606(0.462-0.796)]had a lower probability of diagnosing HIV/AIDS late(P＜0.05).Student patients[OR(95％CI)=1.344(1.187-1.523)],patients infected through same-sex sexual transmission[OR(95％CI)=1.229(1.081-1.397)]and patients receiving testing and counseling[OR(95％CI)=1.218(1.083-1.369)]received their first CD4+T lymphocyte test in a more timely manner(P＜0.05),while patients infected through other routes[OR(95％CI)=0.505(0.361-0.708)]received their first CD4+T lymphocyte test in a less timely manner(P＜0.05).Conclusion Every year,young patients with HIV/AIDS are reported in Hunan Province,among whom there are some patients infected at a younger age.We should make full use of the multiple forces of schools,families and communities to carry out AIDS prevention education,publicity and intervention as early as possible,promote voluntary testing and counseling as well as active testing,and facilitate early detection and early diagnosis.Appropriate follow-up and management care should be conducted to the patients to promote the progress of treatment and reduce secondary transmission.