Observation on the application effect of pleurodesis in surgical treatment of spontaneous pneumothorax in adolescents
LI Jia
ZHAO Qingwu
LI Yongfeng
CHEN Jicai
LIN Yu
Abstract：Objective To observe the application effect of pleurodesis in surgical treatment of spontaneous pneumothorax in adolescents.Methods The clinical data of 187 adolescent patients with spontaneous pneumothorax who underwent video-assisted thoracoscopic bullotomy in Department of Cardiothoracic Surgery,Guangdong Provincial Hospital of Chinese Medicine from January 2014 to December 2022 were retrospectively analyzed.According to the different methods of pleural fixation during the surgery,the patients were divided into pleural friction group(group A,50 cases),talc powder spray group(group B,67 cases)and pleural non-fixation group(group C,70 cases).The perioperative relevant indicators,postoperative adverse events and pneumothorax recurrence were compared among the three groups.Results The surgical treatments were successfully completed in all the patients.The operative time of group C was significantly shorter than that of group A(P＜0.05),and the length of hospitalization in group C was significantly shorter than that in group B(P＜0.05).Compared with group A and group B,group C had less intraoperative blood loss,less postoperative drainage volume and lower usage rate of postoperative analgesics,and shorter time of chest tube placement after surgery,and the differences were statistically significant(P＜0.05).There were no significant differences between group A and group B in the operative time,intraoperative blood loss,postoperative drainage volume and usage rate of postoperative analgesics,time of chest tube placement after surgery and the length of hospitalization(P＞0.05).In group A,2 patients needed a second operation for hemostasis due to hemorrhage in the pleural cavity,and in group B,5 patients developed massive pleural effusion on the affected side 4 weeks after surgery.No adverse events were observed in group C.During the follow-up period,there were 2 cases(4.00％),3 cases(4.48％)and 1 case(1.43％)of recurrent pneumothorax in group A,group B and group C,respectively,and there was no significant difference in the recurrence rate among the three groups(x2=1.162,P=0.559).Conclusion For adolescents with spontaneous pneumothorax,video-assisted thoracoscopic bullotomy combined with pleurodesis can not reduce the recurrence rate of pneumothorax and may increase the risk of adverse events.
Keywords：Spontaneous pneumothoraxAdolescentsPleurodesisVideo-assisted thoracoscopic surgery
Publication Date：2025-03-30
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 319-322 )