Research progress in targeted therapy for HER2-positive breast cancer
WU You
DAI Jianguo
Abstract：Breast cancer is a malignant tumor with a relatively high incidence in women worldwide.In breast cancer patients,human epidermal growth factor receptor 2(HER2)-positive breast cancer cases account for 20％to 30％of the total breast cancer cases,and compared with the other molecular types of breast cancer,HER2-positive breast cancer has a worse prognosis and is more prone to recurrence and metastasis.In recent years,the treatment of HER2-positive breast cancer has attracted much attention,the anti-HER2-targeted drugs can significantly improve the therapeutic effect of HER2-positive breast cancer patients.In this paper,the research progress in targeted therapy for HER2-positive breast cancer is reviewed.
Keywords：Breast cancerHuman epidermal growth factor receptor 2(HER2)-positiveTargeted therapyMolecular mechanismMonoclonal antibody
Publication Date：2024-10-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1183-1186 )