Observation on the therapeutic effect of AcoStream Thrombectomy System combined with catheter directed thrombolysis in treatment of lower extremity deep venous thrombosis with iliac vein compression syndrome
SUO Feifei
LI Jingjing
ZHAI Gang
PANG Hongyong
TIAN Ke
Abstract：Objective To observe the therapeutic effect of AcoStream Thrombectomy System combined with catheter directed thrombolysis(CDT)in treatment of lower extremity deep venous thrombosis(LDVT)with iliac vein compression syndrome(IVCS).Methods The clinical data of 71 patients having LDVT with IVCS who were admitted to First People's Hospital of Shangqiu from June 2020 to December 2022 were retrospectively analyzed.The patients were divided into observation group(receiving treatment of AcoStream Thrombectomy System combined with CDT,29 cases)and control group(receiving treatment of CDT,42 cases)according to different treatment regimens.The stent implan-tations,changes in hemoglobin(Hb)values before and after surgery,dosage of urokinase,length of hospital stay,peak time of D-dimer,clearance rate of thrombus,difference in thigh circumference,difference in calf circumference and Villalta scores were compared between the two groups.Results The dosage of urokinase in the observation group was lower than that in the control group,and the changes in Hb values before and after surgery in the observation group were larger than those in the control group,and the length of hospital stay and the peak time of D-dimer in the observation group were shorter than those in the control group,and the differences were statistically significant(P＜0.05).The throm-bolysis grade in the observation group was better than that in the control group,and the clearance rate of thrombus in the observation group was higher than that in the control group,and the Villalta scores in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).The difference in thigh circumference and the difference in calf circumference 6 months after operation in both groups were significantly decreased compared with those before operation in both groups(P＜0.05),but the differences were not statistically significant between the two groups(P＞0.05).Conclusion AcoStream Thrombectomy System combined with CDT is definitely effective in treating LDVT with IVCS,with lower risk of hemorrhage and significant symptom relief for the patients.
Keywords：Lower extremity deep venous thrombosis(LDVT)Iliac vein compression syndrome(IVCS)AcoStream Thrombectomy SystemCatheter directed thrombolysis(CDT)
Publication Date：2024-08-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 920-924 )