Research progress on target antigens and specific treatment strategies of membranous nephropathy
LU Luying
HAN Fei
Abstract：Membranous nephropathy is one of the most common primary glomerular diseases.The discovery of disease-specific target antigens such as M-type phospholipase A2 receptor(PLA2R)has opened up new ideas for the diagnosis and treatment of membranous nephropathy,especially providing a basis for the intervention of B-cell lineages.The core of treatment is to reduce antibody production and subepithelial immune complex deposition.This paper explores promising targeted therapy methods starting from the specific target antigens of membranous nephropathy.
Keywords：Membranous nephropathyTarget antigenB-cell therapy
Publication Date：2024-08-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 841-845 )