Analysis on clinicopathological features of 6 types of rare uterine mesenchymal tumors based on clinical practice
XIE Le
ZENG Min
LI Hongling
XU Yuanyuan
HUANG Yingxin
WEI Xuxuan
ZHANG Jinhui
MAO Rongjun
Abstract：Objective To explore the clinicopathological features of rare uterine mesenchymal tumors.Methods The case data of rare and intractable uterine mesenchymal tumors definitely diagnosed in Foshan Hospital of Traditional Chinese Medicine from January 2020 to May 2024 were collected.According to the proposed criteria of rare and intrac-table pathological changes in the Department of Pathology,Foshan Hospital of Traditional Chinese Medicine,6 types of rare uterine mesenchymal tumors were collected,and the relevant literature was summarized and analyzed.Results In this study,six lesions[including leiomyoma combined with lipoblastoma,pleomorphic adenoma gene 1(PLAG1)rear-ranged fibromyxoid sarcoma,embryonal neuroectodermal tumor/central type primitive neuroectodermal tumor,unspecified DICER1 mutation-related sarcoma,composite uterine high-grade sarcoma with embryonal rhabdomyosarcoma and fibro-sarcoma and neuroectodermal differentiation,and MXI1-NUTM1 fusion sarcoma]were selected and the features of their clinical,morphological,immunohistochemical and molecular detection results were described.Conclusion Uterine mesenchymal tumors are relatively rare,but various types of mesenchymal tumors originating outside the uterus still occur in the uterus,and due to some limitations in sub-specialty grading diagnosis of clinical pathology,there is a potential risk of misdiagnosis and missed diagnosis,and accurate diagnosis of these mesenchymal tumors relies on the compre-hensive evaluation of their clinical,morphological,immunohistochemical and molecular detections.
Keywords：Uterine tumorMesenchymal tumorMolecular geneticsRare and intractable pathological changes
Publication Date：2024-07-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 733-739 )