Comparison of differences in responses to laparoscopic surgery under intubation general anesthesia among patients with different constitutions of Traditional Chinese Medicine

TANG Xiaoxiao; PENG Li; ZHANG Yongchao

doi:10.3969/j.issn.1674-3806.2024.06.15

Abstract：Objective To compare the differences in responses to laparoscopic surgery under intubation general anesthesia among patients with different constitutions of Traditional Chinese Medicine.Methods One hundred and nineteen patients who underwent laparoscopic abdominal surgery under intubation general anesthesia in Nanning Hospital of Tra-ditional Chinese Medicine from January 2019 to September 2022 were recruited.According to the Classification and Judgment of Traditional Chinese Medicine Constitutions(ZYYXH-T157-2009),the patients were divided into gentle con-stitution group(50 cases),Yang deficiency constitution group(36 cases)and Qi deficiency constitution group(33 cases).The mean arterial pressure,heart rate,propofol dosage during anesthesia maintenance and the incidence of adverse reactions were compared among the three groups 5 minutes before anesthesia induction(T,),at intubation(T2),and 5 minutes after intubation(T3).Results From the time point of T1 to the time point of T3,the mean arterial pressure and heart rate showed a downward trend in the three groups.At the time point of T2,the mean arterial pressure in the Yang deficiency constitution group was significantly higher than that in the gentle constitution group and the Qi deficiency constitution group(P＜0.05).There was no significant difference in the mean arterial pressure among the three groups at the time point of T,and the time point of T3(P＞0.05).There was no significant difference in the heart rate among the three groups at the time point of T1 to the time point of T3(P＞0.05).The propofol dosage in the gentle constitution group and the Yang deficiency constitution group was significantly higher than that in the Qi deficiency constitution group(P＜0.05),but there was no statistically significant difference between the gentle constitution group and the Yang deficiency constitution group(P=0.100).The incidence of hypotension in the Qi deficiency constitution group was significantly higher than that in the gentle constitution group and the Yang deficiency constitution group(P＜0.05).The incidence of nausea and vomiting in the gentle constitution group was significantly lower than that in the Yang deficiency constitution group and the Qi deficiency constitution group(P＜0.05).There was no significant difference in the incidence of brad-ycardia among the three groups(P＞0.05).Conclusion Patients with different constitutions of Traditional Chinese Medicine have different responses to laparoscopic surgery under intubation general anesthesia,and clinicians should conduct classified management for the patients.