Research progress of pyroptosis in rheumatoid arthritis
WANG Jiani
ZHOU Dianyou
WU Lijuan
Abstract：Rheumatoid arthritis(RA)is an autoimmune disease characterized by synovitis and progressive joint destruction.At present,the pathogenesis of RA is unclear,and pyroptosis,as a newly discovered programmed cell death,has been confirmed to promote the development of RA by releasing pro-inflammatory mediators through intra-cellular kinase interactions.This paper reviews the research progress of pyroptosis in RA.
Keywords：Rheumatoid arthritis(RA)PyroptosisInflammasomeGasdermin(GSDM)protein family
Publication Date：2024-05-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 585-589 )