Analysis on the correlation of preoperative LAA opening parameters with the size of the occluders placed intra-operatively in AF patients undergoing LAAO and the factors influencing the occurrence of postoperative PDL
CHAI Xianing
WANG Xinwen
YANG Min
ZHAO Jimin
WANG Jie
DING Jinxiang
GAO Nanlin
Abstract：Objective To analyze the correlation of preoperative left atrial appendage(LAA)opening parameters with the size of the occluders placed intraoperatively in atrial fibrillation(AF)patients undergoing left atrial appendage occlusion(LAAO)and the factors influencing the occurrence of postoperative peri-device leak(PDL).Methods The clinical data of 83 patients with non-valvular AF who were successfully treated with LAAO in Second Hospital of Shanxi Medical University from January 2019 to December 2022 were retrospectively analyzed.The patients were divided into PDL group(23 cases)and non-PDL group(60 cases)according to the occurrence of postoperative PDL.The clinical data and LAA opening parameters were compared between the patients in the two group.Pearson correlation was used to analyze the correlation of LAA opening parameters with the size of the occluders placed intraoperatively in the non-PDL group.Logistic regression was used to analyze the factors influencing the occurrence of postoperative PDL.Results The patients in the PDL group were significantly younger than those in the non-PDL group(P＜0.05).There were no statistically significant differences in gender and combined underlying diseases between the two groups(P＞0.05).The long diameter,short diameter,circumference and area of the LAA opening in the PDL group were greater than those in the non-PDL group,and the differences were statistically significant(P＜0.05).The results of Pearson correlation analysis showed that the long diameter,short diameter,circumference and area of the LAA opening in the non-PDL group were positively correlated with the size of the placed occluders(P＜0.05).The results of multivariate logistic regression analysis showed that older age was an independent protective factor for the occurrence of postoperative PDL(P＜0.05),and larger short diameter of LAA opening was an independent risk factor for the occurrence of postoperative PDL(P＜0.05).Conclusion LAA opening parameters are positively correlated with the size of occluders,and the LAA opening area has the best correlation with the size of the occluders,which provides guidance for the selection of occluders in clinical practice.Older age is an independent protective factor for the occurrence of PDL after LAAO and larger short diameter of LAA opening is an independent risk factor for the occurrence of PDL after LAAO.
Keywords：Left atrial appendage computed tomography(CT)imagingAtrial fibrillation(AF)Left atrial appendage(LAA)occlusion(LAAO)Peri-device leak(PDL)Left atrial appendage opening
Publication Date：2024-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 432-436 )