A study on the correlation of obesity with postoperative complications and re-operation in patients with vestibular schwannoma
LI Wenzhuang
WANG Zening
LI Yandong
ZHU Guohua
Maidinaimu Mahemuti
Maimaitili Mijiti
Geng Dangmurenjiafu
Abstract：Objective To explore the correlation of obesity with postoperative complications and re-operation in patients with vestibular schwannoma(VS).Methods The clinical and imaging data of 377 patients with VS who under-went retrosigmoid approach surgery in the First Teaching Hospital of Xinjiang Medical University from June 2013 to June 2023 were retrospectively analyzed.According to body mass index(BMI),the patients were divided into obese group(BMI ≥28 kg/m2,91 cases)and non-obese group(BMI＜28 kg/m2,286 cases).The clinical data,the incidence rate of postoperative complications and the re-operation rate were compared between the two groups.The influence of BMI on postoperative cerebrospinal fluid leakage and re-operation was explored by using multivariate logistic regression analysis.Results Compared with the non-obese group,the obese group had higher proportion of male sex,patients complicated with diabetes mellitus and hypertension,and the difference was statistically significant(P＜0.05).There were no sig-nificant differences in age,hospitalization time,operation side,tumor nature,tumor volume grade and operation time between the two groups(P＞0.05).The incidence rate of postoperative cerebrospinal fluid leakage and the re-operation rate in the obese group were higher than those in the non-obese group,and the differences were statistically significant(P＜0.05).There were no significant differences in the incidence rates of intracranial hemorrhage,incision infection,intracranial infection,deep vein thrombosis and other postoperative complications between the two groups(P＞0.05).After adjusting for age,sex,tumor volume grade and tumor nature,the results of multivariate logistic regression analysis showed that higher BMI level was a risk factor for postoperative cerebrospinal fluid leakage[OR(95％CI)=1.168(1.051-1.299),P=0.004]and re-operation[OR(95％CI)=1.160(1.053-1.277),P=0.003].Conclusion Obesity is closely related to postoperative cerebrospinal fluid leakage and re-operation in VS patients,and the increased BMI is a risk factor for postoperative cerebrospinal fluid leakage and re-operation.
Keywords：Vestibular schwannoma(VS)ObesityPostoperative complicationCerebrospinal fluid leakageRe-operation
Publication Date：2024-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 427-431 )