An investigation on clinical application of orbital color Doppler imaging in diagnosis of central retinal artery occlusion

HUANG Chan-juan; LI Pei-jing; YAUN Rong-di

doi:10.3969/j.issn.1674-3806.2023.12.12

Abstract：Objective To investigate the clinical application value of orbital color Doppler imaging(OCDI)in diagnosis of central retinal artery occlusion.Methods The clinical data of 34 patients(34 eyes)with central retinal artery occlusion who were admitted to the Second Affiliated Hospital of Army Medical University from January 2015 to Sep-tember 2021 were selected,including15 patients(15 eyes)aged＜60 years and19 patients(19 eyes)aged≥60 years.Other 30 healthy subjects(30 eyes)during the same period were included as the control group.The hemodynamics indi-cators of the central retinal artery in the affected eyes and the healthy eyes of the patients were detected using OCDI,including peak systolic velocity(PSV),end diastolic velocity(EDV),resistance index(RI)and pulsatility index(PI).Kappa consistency test was used to analyze the consistency between the findings of fluorescein fundus angiography(FFA)and the findings of OCDI.The clinical features of the patients with central retinal artery occlusion whose OCDI was neg-ative were analyzed.Results The PSV and EDV levels in the affected eyes of the patients with central retinal artery occlusion were lower than those in the healthy eyes,and the RI and PI levels in the affected eyes were higher than those in the healthy eyes,and the differences were statistically significant(P＜0.05).The PI level in the affected eyes of the central retinal artery occlusion patients aged≥60 years was significantly higher than that in the affected eyes of the patients in the control group(P＜0.05),but there was no significant difference in the PI level between the affected eyes and the healthy eyes of the central retinal artery occlusion patients(P＞0.05).There were no significant differ-ences in the indicators of PSV,EDV and RI among the affected eyes,the healthy eyes and the control group(P＞0.05).For the central retinal artery occlusion patients aged＜60 years,the levels of PSV and EDV in the affected eyes were significantly lower than those in the healthy eyes and the control group(P＜0.05),and the levels of PI and RI were higher than those in the control group(P＜0.05),but there was no statistically significant difference between the patients and the healthy eyes(P＞0.05).OCDI and FFA had good consistency in the diagnosis of central retinal artery occlu-sion(Kappa =0.807,P＜0.001).The time from onset to visiting the doctor in the patients with negative OCDI diag-nosis was later than that of the patients with positive OCDI diagnosis(P＜0.05),and the difference was statistically significant(P＜0.05).There were no significant differences in PSV,EDV and RI between the affected eyes and the healthy eyes of the patients with negative OCDI diagnosis(P＞0.05).Conclusion The hemodynamics of central ret-inal artery in patients with central retinal artery occlusion are significantly changed.OCDI examination is helpful for early diagnosis of central retinal artery occlusion.