The evolution of prognostic and predictive markers in breast cancer
Hani Katerji
Huina Zhang
David G.Hicks
Bradley M.Turner
Abstract：Breast cancer is the most frequent cause of cancer death in women living in less developed regions of the world, and the second leading cause of cancer death in women living in more well-developed regions of the world. Breast cancer treatment options continue to evolve, with multiple treatment modalities now available;however, finding reliable predictive and prognostic biomarkers that will aid in selecting the appropriate treatment for breast cancer patients who would most likely respond to a specific therapy is still a major challenge, and has been the focus of many research groups throughout the past few decades. In this review, we attempt to provide an overview of the current prognostic and predictive markers in breast cancer including traditional, immunohistochemical, and genomic assays, and assess the potential clinical use of these markers.
Keywords：Breast cancerPrognosisPredictionBiomarkersEvolution
Publication Date：2021-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：13( 1169-1181 )