Clinical observation of Shenqiyixin decoction on chronic congestive heart failure in patients with normal ejection fraction
LIU Jing-mei
LI Yu-xian
Abstract：Objective To investigate the effect of Shenqiyixin decoction on chronic congestive heart failure in patients with normal ejection fraction.Methods Ninety-four patients who were diagnosed with chronic congestive heart failure but with normal ejection fraction were selected, and were randomly divided into Chinese Medicine group and Western Medicine group, with 47 cases in each group.The Chinese Medicine group was treated with Traditional Chinese Medicine Shenqiyixin decoction.The Western Medicine group was treated with nitroglycerin, diuretic and angiotensin-converfing enzyme inhibitor (ACEI), with 4 weeks for a course and a total of 3 courses of treatment.The changes of clinical indexes of left ventricular function and plasma NT-proBNP levels during and after treatment, and the curative effect were compared between the two groups.ResultsThe levels of LVEF, PEF after treatment were obviously higher than those before treatment in the two group, while the levels of TPER were obviously lower than those before treatment (P＜0.05).The levels of LVEF and PEF were obviously higher and the level of TPER was obviously shorter in the Chinese Medicine group than those in the Western Medicine group (P＜0.05).There were no significant differences in the plasma levels of NT-proBNP between the two groups before treatment, but they were significantly reduced in both of the two groups after treatment (P＜0.05).The improvement of NT-proBNP in the Chinese Medicine group was better than that in the Western Medicine group (P＜0.05).In the Chinese Medicine group, 26 cases were markedly effective, 18 cases effective and 3 cases ineffective.In the Western Medicine group, 17 cases were markedly effective, 21 cases effective and 9 cases ineffective.The curative effect of the Chinese Medicine group was better than that of the Western Medicine group (P＜0.05).Conclusion Modified Shenqiyixin decoction is effective on chronic congestive heart failure and improves cardiac function and increases activity tolerance in the patients who are diagnosed with chronic congestive heart failure but with normal ejection fraction.
Keywords：Shenqiyixin decoctionLeft ventricular ejection fraction (LVEF)Chronic congestive heart failure
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 66-69 )